The effect of stromal cell-derived factor 1 (SDF1/CXCL12) genetic polymorphism on HIV-1 disease progression
نویسندگان
چکیده
منابع مشابه
The Role of Genetic Variants of Stromal Cell-Derived Factor 1 in Pediatric HIV-1 Infection and Disease Progression
Stromal cell-Derived Factor 1 (SDF1) is the natural ligand of CXCR4, the coreceptor of HIV-1 X4 viruses. This study investigated the role of the single nucleotide polymorphism (SNP) rs1801157 (NM_000609.5:c.*519G>A) of the SDF1 gene in the natural history of mother-to-child transmission of HIV-1 and disease progression of HIV-1-infected children. The study was conducted in 428 children born to ...
متن کاملStromal Cell Derived Factor-1 Genetic Variation at Locus 801 in Patients with Myasthenia Gravis
Background: Myasthenia gravis (MG) is the most common disorder of neuromuscular junction in which autoantibodies develop against nicotinic acetylcholine receptor for unknown reasons. The association of immunomodulator genes with different autoimmune disease has been studied in recent years. Objective: The aim of this study was to investigate correlation between a genetic variation in Stromal Ce...
متن کاملStromal Cell-Derived Factor 1 Polymorphism in Retinal Vein Occlusion
BACKGROUND Stromal cell-derived factor 1 (SDF1) has crucial role in the regulation of angiogenesis and ocular neovascularisation (NV). The purpose of this study was to evaluate the association between SDF1-3'G(801)A polymorphism and NV complications of retinal vein occlusion (RVO). METHODS 130 patients with RVO (median age: 69.0, range 35-93 years; male/female- 58/72; 55 patients had central ...
متن کاملStromal cell-derived factor 1 polymorphism in patients infected with HIV and implications for AIDS progression in Tunisia
BACKGROUND An interesting finding in the epidemiology of human immunodeficiency virus (HIV) infection is that certain mutations in genes coding for chemokines, and their receptors and ligands, may confer resistance or susceptibility to HIV-1 infection and acquired immunodeficiency syndrome (AIDS) progression. The mutation most frequently studied is stromal cell-derived factor (SDF)1-3'A, a sing...
متن کاملstromal cell derived factor-1 genetic variation at locus 801 in patients with myasthenia gravis
background: myasthenia gravis (mg) is the most common disorder of neuromuscular junction in which autoantibodies develop against nicotinic acetylcholine receptor for unknown reasons. the association of immunomodulator genes with different autoimmune disease has been studied in recent years. objective: the aim of this study was to investigate correlation between a genetic variation in stromal ce...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2006
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.18.4.785